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Contrast: Contrast and Other Medications Imaging Pearls - Educational Tools | CT Scanning | CT Imaging | CT Scan Protocols - CTisus
Imaging Pearls ❯ Contrast ❯ Contrast and Other Medications

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  • “Extrinsic warming of iodinated contrast material to human body temperature (37oC) may be helpful to minimize complications and improve vascular opacification in the following circumstances:
    - For high-rate (>5 mL/second) IV LOCM power injections
    - For injections of viscous iodinated contrast (e.g., iopamidol 370, and presumably other contrast media with a similar or higher viscosity)
    - For direct arterial injections through small-caliber catheters (5 French or smaller)
    - For intravenously injected arterial studies in which timing and peak enhancement are critical features”
    ACR Manual on Contrast Media
    Version 9 (2013)
  • "Documented cases of lactic acidosis in patients who were taking metformin and had normal baseline renal function and who received a usual dose of ICM when a single CT scan was obtained or cases in which the contrast medium was identified as the sole cause for LA could not be identified."

    Systematic Review of Current Guidelines, and Their Evidence Base, on Risk of Lactic Acidosis after Administration of Contrast Medium for Patients Receiving Metformin
    Goergen SK et al.
    Radiology 2010; 254:261-269

  • "This finding may obviate the need to advise patients in this situation to stop taking metformin, which would potentially entail the risk that they fail to recommence it and thus increase their cardiovascular risk and worsens control of their blood glucose level."

    Systematic Review of Current Guidelines, and Their Evidence Base, on Risk of Lactic Acidosis after Administration of Contrast Medium for Patients Receiving Metformin
    Goergen SK et al.
    Radiology 2010; 254:261-269

     

  • "No evidence could be found to support the recommendation to cease metformin administration and/or to retest kidney function before recommencing metformin in patients with normal baseline kidney function who undergo a single examination involving ICM if contrast medium volumes exceeding those usually used for CT scanning are not used in the single examination."

    Systematic Review of current Guidelines, and Their Evidence Base, on Risk of Lactic Acidosis after Administration of Contrast Medium for Patients Receiving Metformin
    Goergen SK et al.
    Radiology 2010; 254:261-269

  • "There is no evidence that there is an increased risk of lactic acidosis in patients taking metformin who have stable normal renal function and who received a single dose of contrast medium, a usual amount for that used in CT scanning or other nonangiographic procedures."

    Systematic Review of current Guidelines, and Their Evidence Base, on Risk of Lactic Acidosis after Administration of Contrast Medium for Patients Receiving Metformin
    Goergen SK et al.
    Radiology 2010; 254:261-269

  • "Substantial inconsistencies exist between the recommendations ot the five international guidelines about contrast medium administration in patients who are taking metformin. These are in part, caused by the low level of evidence underpinning guideline recommendations."

    Systematic Review of current Guidelines, and Their Evidence Base, on Risk of Lactic Acidosis after Administration of Contrast Medium for Patients Receiving Metformin
    Goergen SK et al.
    Radiology 2010; 254:261-269

  • “ Substantial inconsistencies exist between the recommendations ot the five international guidelines about contrast medium administration in patients who are taking metformin. These are in part, caused by the low level of evidence underpinning guideline recommendations.”

    Systematic Review of current Guidelines, and Their Evidence Base, on Risk of Lactic Acidosis after Administration of Contrast Medium for Patients Receiving Metformin
    Goergen SK et al.
    Radiology 2010; 254:261-269
  • “ There is no evidence that there is an increased risk of lactic acidosis in patients taking metformin who have stable normal renal function and who received a single dose of contrast medium, a usual amount for that used in CT scanning or other nonangiographic procedures.”

    Systematic Review of current Guidelines, and Their Evidence Base, on Risk of Lactic Acidosis after Administration of Contrast Medium for Patients Receiving Metformin
    Goergen SK et al.
    Radiology 2010; 254:261-269
  • “ No evidence could be found to support the recommendation to cease metformin administration and/or to retest kidney function before recommencing metformin in patients with normal baseline kidney function who undergo a single examination involving ICM if contrast medium volumes exceeding those usually used for CT scanning are not used in the single examination.”

    Systematic Review of current Guidelines, and Their Evidence Base, on Risk of Lactic Acidosis after Administration of Contrast Medium for Patients Receiving Metformin
    Goergen SK et al.
    Radiology 2010; 254:261-269
  • “ This finding may obviate the need to advise patients in this situation to stop taking metformin, which would potentially entail the risk that they fail to recommence it and thus increase their cardiovascular risk and worsens control of their blood glucose level.”

    Systematic Review of Current Guidelines, and Their Evidence Base, on Risk of Lactic Acidosis after Administration of Contrast Medium for Patients Receiving Metformin
    Goergen SK et al.
    Radiology 2010; 254:261-269
  • “ Documented cases of lactic acidosis in patients who were taking metformin and had normal baseline renal function and who received a usual dose of ICM when a single CT scan was obtained or cases in which the contrast medium was identified as the sole cause for LA could not be identified.”

    Systematic Review of Current Guidelines, and Their Evidence Base, on Risk of Lactic Acidosis after Administration of Contrast Medium for Patients Receiving Metformin
    Goergen SK et al.
    Radiology 2010; 254:261-269
  • "Pulmonary embolism is a leading cause of maternal mortality in pregnant patients."

    Venous Thromboembolism During Pregnancy
    Toglia MR et al.
    N Engl J Med 1996; 335:108-114

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