- Ulcerative Colitis and Colon Cancer: Facts
- Risk increases after disease present for 8-10 years and correlates with extent of disease
- Best estimates of risk are 5% after 10-20 years of disease and 9% per year thereafter
- Because biopsies are necessary in screening these patients for dysplasia CTC is not used but classic colonoscopy is needed - Colorectal Cancer: Risk Categories
- 1. average risk (age of 50 years old)
- 2. moderate risk (first degree relative with a history of adenoma or carcinoma or personal history of adenoma or carcinoma)
- 3. high risk (hereditary syndromes like familial polyposis, personal history of ulcerative colitis or Crohn’s disease) - Why do we do Colon Cancer screening?
- The prevalence of adenomas in the general population is 30-50% and increases with age
- The vast majority of adenomas are <1cm and these lesions have about a 1% likelihood of containing invasive cancer.
- Only 1-3% of adenomas ever progress to cancer
- Adenomas >1 cm have have a 10% chance of containing invasive cancer and a 25% chance of progressing to invasive cancer over 20 years
- Approximately 8% may undergo malignant degeneration within 10 years - ACR Appropriateness Criteria on Colorectal Cancer Screening: Summary Statements
- Computed tomographic colonography has emerged as the leading imaging technique for colorectal cancer screening
- The DCBE remains an imaging test that is also appropriate for colorectal cancer screening, particularly when CTC is not available
- Computed tomographic colonography is the preferred test after incomplete colonoscopy
- Imaging tests, including CTC and barium enema, are usually not appropriate for colorectal cancer screening in high risk patients with hereditary nonpolyposis colrectal cancer and inflammatory bowel disease - Ulcerative Colitis and Colon Cancer: Facts
- Risk increases after disease present for 8-10 years and correlates with extent of disease
- Best estimates of risk are 5% after 10-20 years of disease and 9% per year thereafter
- Because biopsies are necessary in screening these patients for dysplasia CTC is not used but classic colonoscopy is needed - Colorectal Cancer: Risk Categories
- 1. average risk (age of 50 years old)
- 2. moderate risk (first degree relative with a history of adenoma or carcinoma or personal history of adenoma or carcinoma)
- 3. high risk (hereditary syndromes like familial polyposis, personal history of ulcerative colitis or Crohn’s disease)
- Why do we do Colon Cancer screening?
- The prevalence of adenomas in the general population is 30-50% and increases with age
- The vast majority of adenomas are <1cm and these lesions have about a 1% likelihood of containing invasive cancer.
- Only 1-3% of adenomas ever progress to cancer
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