- Complications of Aortic Valve Replacement
- Paravalvular or valvular regurgitation
- Dehiscence
- Endocarditis and abscess formation
- Valve obstruction (thrombus and pannus)
- Structural failure
- Pseudoaneurysm formation
- Aortic dissection
- Hemolysis
- “PhyZiodynamics, a non-rigid registration based algorithm, introduces an opportunity to re-evaluate the CT scan and its role in cardiac imaging, ultimately offering more information- both functional and anatomical- about the heart.”
PhyZiodynamics: A Revolutionary Approach for Post Processed Noise Reduction, Motion Coherence and functional Analytics
H Brown
Ziosoft Inc. - The technique uses a deformable registration model which allows
1. Differentiate noise vs. real data in order to minimize the noise (and hopefully allow dose reduction).
2. Intelligently interpolate additional phases to increase the fidelity of dynamic functional images for greater motion coherence.
3. Enable future functional analytic applications such as surface velocity mapping and multi-modality fusion. - PhyZiodynamic Noise Reduction
-Reduces image noise without compromising spatial resolution
-Post processing technique that can enhance data sets from iterative reconstruction techniques
-Noise reduction is in the 33% range in preliminary studies - Motion Coherence
“PhyZiodynamics allows the user to generate up to 9 additional phases between the original adjacent phases for motion coherence. The supercomputing foundation of PhyZiodynamics processes the computationally intense optical flow algorithm and allows the user to interactively manipulate the 50-phase data set. While PhyZiodynamics does not alter the temporal resolution which is determined at the scanner, it improves the fidelity of biological motion of the cardiac cycle by increasing the frame rate.” - Functional Analytics
With multi-phase data sets, PhyZiodynamics tracks the motion from voxel-to-voxel to calculate displacement, velocity and acceleration. The kinematics are displayed as a parametric map that is overlaid on the volume rendered surface and can be manipulated while in motion providing 5D imaging of the heart "In patients with severe heart failure, LVADs have become a more widely used treatment option as a bridge to heart transplantation, as destination therapy, and as a bridge to myocardial recovery. It is important to have an understanding of the components of such devices and their normal imaging features." CT of Left Ventricular Assist Devices
Carr CM et al.
RadioGraphics 2010; 30:429-444 - Left Ventricular Assist Devices (LVADs): Clinical Use
- As a bridge to heart transplantation
- As destination therapy for patient ineligible to receive a transplant
- As a bridge to myocardial recovery - Complications of Left Ventricular Assist Devices (LVADs)
- Inflow and outflow cannula complications
- Postoperative hemorrhage
- Pericardial tamponade
- Thrombus formation
- Aortic valve stenosis
- Aortic valve insufficiency
- Right sided heart failure
- Infection
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