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Everything you need to know about Computed Tomography (CT) & CT Scanning

State-of-the-art Diagnosis and Treatment of Metastatic Melanoma: MDCT Protocol Optimization to Identify Metastases in Unusual Locations and Review of Innovative Therapeutic Agents

Take-Home Points

  • PET/CT may be more sensitive to identify metastatic melanoma40, but IV contrast enhanced CT is often the first line imaging modality for follow up, underscoring the importance of careful inspection for early metastases.
  • IV contrast, high contrast display windows and MPRs facilitate identification of melanoma metastases
  • Melanoma has a propensity to metastasize to sites not often involved by other malignancies and radiologists’ search patterns must include careful scrutiny of these uncommon locations, as illustrated in this case series.
  • Hemorrhage and small bowel obstruction are suspicious for metastasis in patients with history of melanoma
  • New therapies hold promise in the treatment of melanoma, but the radiologist must be aware of imaging complications such as colitis, pneumonitis, and lymphadenopathy.

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