Body Imaging Section, Division of Diagnostic Imaging, The University of Texas M. D. Anderson Cancer Center, Unit 1476, 1515 Holcombe Blvd, Houston, TX 77030-4009.
OBJECTIVE: A multimodality imaging spectrum of adrenocortical carcinoma, with an emphasis on both anatomic and functional imaging, will be reviewed. Recent advances in the molecular cytogenetics of this tumor and its impact on diagnosis, prognosis, and development of newer targeted therapy will be discussed in this article. CONCLUSION: Adrenocortical carcinomas are rare aggressive tumors associated with a poor prognosis. Awareness of the molecular behavior and spectrum of imaging features of this tumor can help in appropriate patient treatment.