In this issue, Dowe [1] makes his case for screening with coronary computed tomographic angiography (CCTA). Although we believe that CCTA is an impressive technological advancement with valuable clinical applications and tremendous research potential, we disagree with Dowes major premise that the time for screening is near. Nevertheless, we welcome the opportunity to join the discussion and examine the conditions under which screening with CCTA might become feasible some time in the future. In doing so, we consider 10 criteria that have been previously proposed for effective screening [2], the first 2 pertaining to the target disease, the next 5 to the screening test, and the final 3 to the treatment.