Computed tomographic (CT) colonography currently faces the critical challenge of a rapidly evolving technique being validated in generalizable environments.
These environments include the evaluation of the data by less expert readers who have undergone training, with standardized image display and reader protocols.
This article reviews the current image display techniques most widely used, the reader protocol for detection and characterization of colorectal lesions, and standardization issues for reporting findings. Important issues of test performance expectations are also reviewed, which greatly affect the development and optimization of the reading paradigm.