Pheochromocytoma: There is no evidence that IV administration of modern iodinated or gadolinium-based contrast medium increases the risk of hypertensive crisis in patients with pheochromocytoma [12]. Therefore, restricting contrast medium use or premedicating solely on the basis of a history of pheochromocytoma is not recommended. Direct injection of any type of contrast medium into the adrenal or renal arteries in a patient with pheochromocytoma has not been adequately studied and is of unknown risk. ACR Manual On Contrast Media 2023
"IV administration of nonionic contrast material for CT is a safe practice for patients with pheochromocytoma and related tumors even without alpha-blocking medication."
CT of Pheochromocytoma and Paraganglioma: Risk of Adverse Events with IV Administrationof Nonionic Contrast Material Bessell-Browne R et al. AJR 2007; 188:970-974
"Our results and the clinical practice described in the recent literature suggest that alpha-blockade is not specifically required before IV administration of nonionic contrast material to patients with suspected or known pheochromocytoma or related tumors."
CT of Pheochromocytoma and Paraganglioma: Risk of Adverse Events with IV Administrationof Nonionic Contrast Material Bessell-Browne R et al. AJR 2007; 188:970-974
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