CT colonography is a rapidly evolving technique for detection of col-orectal neoplasia [1]. Although the performance characteristics of CT colonography have been encouraging in populations with above-average risk for polyps, its utility for screening an average-risk population remains unproven [1-3]. Most studies to date have relied on the two-dimensional (2D) CT images for primary polyp detection, reserving the three-dimensional (3D) rendering for confirmation or problem solving [1]. A recognized advantage of 3D CT colonography over 2D imaging is its improved depiction of surface morphology, particularly in distinguishing polypoid lesions from haustral folds [4]. The main barrier to primary 3D endoluminal imaging has been its time-consuming nature [5].
