| The American College of Radiology (ACR) Manual on Contrast Media lists altered taste as a mild adverse reaction to contrast media. A mild reaction, as described by the ACR Manual on Contrast Media, is self-limited without evidence of progression. Some patients may experience a “metallic” taste after the intravenous injection of a contrast agent. Taste dysfunction, or “metallic” taste, can occur because some pharmaceutical agents have sufficiently high plasma concentrations to stimulate taste receptors from the basolateral side (plasma membrane) of taste cells. According to the ACR Manual on Contrast Media, this reaction should be observed to confirm resolution and/or lack of progression but usually does not require treatment. |